Selective Applications of Comprehensive Two-Dimensional Gas Chromatography

Date/Time/Location	Event Description	CLP?
Thu., Jan. 29, 2009, 4pm Plyler 249	Paper Presentation: "Selective Applications of Comprehensive Two-Dimensional Gas Chromatography" Speaker: Jean-Marie D. Dimandja	No

ABSTRACT:

Comprehensive two-dimensional gas chromatography (GCxGC) is an emerging separation science technology in which a tandem set of GC columns are interfaced through an on-column inlet device (called a modulator) that sequentially introduces sample effluent fractions from the first column into the second column. The first dimension chromatogram is operated at similar conditions as in conventional GC, and the second dimension is operated at high-speed conditions that produce a secondary chromatogram every few seconds on average. The ensemble of the series high-speed secondary chromatograms are then assembled to form a virtual multi-dimensional chromatogram in which each separated substance can be identified by their retention coordinates.

GCxGC is capable of producing high-resolution separations in a time frame similar to that obtained by conventional GC, while providing peak capacities that are 2-3 orders of magnitude higher than in 1D GC, thus improving the information throughput for the analyst. In addition, GCxGC chromatograms have revealed the structured nature of the molecular world, which offers great potential in the fingerprinting of new or unknown substances in a variety of samples such as in meteorites that contain substances of extra-terrestrial origin. In this presentation an overview of the instrumentation will be given, and application in industrial, environmental and bioanalytical chemistry that have been developed in our laboratory will also be presented.